Friday, September 16, 2016

ciprofloxacin and hydrocortisone otic


Generic Name: ciprofloxacin and hydrocortisone otic (sih pro FLOCK sah sin and hye droe CORE tih sone OH tic)

Brand Names: Cipro HC


What is ciprofloxacin and hydrocortisone otic?

Ciprofloxacin is a fluoroquinolone antibiotic. Ciprofloxacin fights bacteria in the body.


Hydrocortisone is a steroid. It is used with ciprofloxacin to reduce inflammation caused by an infection.


Together, ciprofloxacin and hydrocortisone are used to treat ear infections.


Ciprofloxacin and hydrocortisone otic may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about ciprofloxacin and hydrocortisone otic?


Do not use this medication in the eyes or take it by mouth. Ciprofloxacin and hydrocortisone otic is intended for use in the ears only. Do not touch the dropper opening to any surface, including the ears or hands. The dropper opening is sterile. If it becomes contaminated, it could cause another infection in the ear.

Notify your doctor if the condition does not improve or appears to worsen.


What should I discuss with my healthcare provider before using ciprofloxacin and hydrocortisone otic?


Do not use ciprofloxacin and hydrocortisone otic if the ear drum (tympanic membrane) has ruptured (broken). It may be dangerous for medicine to get into the inner ear. A ruptured ear drum usually causes a considerable amount of pain. A decrease in hearing may also occur. Call your doctor if you suspect a ruptured ear drum. Your doctor will know if the ear drum is ruptured by looking into the ear with a special device (otoscope). Do not use ciprofloxacin and hydrocortisone otic without first talking to your doctor if you have had a previous allergic reaction to it or to another similar oral or topical medication such as:

  • a fluoroquinolone antibiotic such as ciprofloxacin (Cipro), gatifloxacin (Tequin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), ofloxacin (Floxin), sparfloxacin (Zagam), or trovafloxacin (Trovan);




  • an oral or injectable steroid such as cortisone (Cortef, Cortone), dexamethasone (Decadron), hydrocortisone (Hydrocortone), methylprednisolone (Medrol), prednisolone (Prelone, Pediapred), prednisone (Orasone, Deltasone), and others; or




  • a topical steroid such as betamethasone (Diprosone, Diprolene), clobetasol (Temovate, Olux), fluocinolone (Synalar, Synemol, Fluonid), fluocinonide (Lidex), fluticasone (Cutivate), halobetasol (Ultravate), mometasone (Elocon), triamcinolone (Aristocort), and others.



You may not be able to use ciprofloxacin and hydrocortisone otic, or you may require a dosage adjustment or special monitoring during treatment.


Ciprofloxacin and hydrocortisone otic is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not use ciprofloxacin and hydrocortisone otic without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether ciprofloxacin and hydrocortisone otic passes into breast milk. Do not use ciprofloxacin and hydrocortisone otic without first talking to your doctor if you are breast-feeding a baby.

How should I use ciprofloxacin and hydrocortisone otic?


Use ciprofloxacin and hydrocortisone otic exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. Do not use this medication in the eyes or take it by mouth. Ciprofloxacin and hydrocortisone otic is intended for use in the ears only.

In general, ciprofloxacin and hydrocortisone otic should be used as follows:



  • Warm the drops slightly by holding them in the hands for 1 or 2 minutes. Administration of cold drops into the ear may cause dizziness.




  • Have another person administer the drops whenever possible. Have the affected person lie on their side or tilt the ear up to make administering a drop easier.



  • Gently shake the drops just before administration.


  • For adults, hold the earlobe up and back. For children, hold the earlobe down and back. This will allow the drops to run into the ear canal. Carefully instill the prescribed number of drops in the first ear.




  • Keep the ear tilted for approximately 30 to 60 seconds to allow the medication to penetrate the ear.




  • Repeat the process in the other ear if prescribed.



Use all of the medication that has been prescribed. Symptoms may begin to improve before the condition is completely treated. If you do not use all of the medication prescribed, the condition could return or worsen.


It is important to use ciprofloxacin and hydrocortisone otic regularly to get the most benefit.


Notify your doctor if the condition does not improve or appears to worsen.


Avoid getting water inside of the affected ear(s) during treatment with ciprofloxacin and hydrocortisone. Care should be used while bathing and swimming may not be recommended. Talk to your healthcare provider.

Store ciprofloxacin and hydrocortisone otic at room temperature or in the refrigerator, away from moisture, heat, and direct light. Keep the bottle properly capped. Do not allow the medication to freeze.


What happens if I miss a dose?


Use the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and use only the next regularly scheduled dose. Do not use a double dose of ciprofloxacin and hydrocortisone otic unless otherwise directed by your doctor.


What happens if I overdose?


Seek emergency medical attention if an overdose is suspected or if the medication has been ingested.

Symptoms of a ciprofloxacin and hydrocortisone otic overdose are not known.


What should I avoid while using this medication?


Ear infections may sometimes cause dizziness or a loss of balance. Use caution when driving, operating machinery, or performing other hazardous activities if you experience dizziness or a loss of balance. Avoid getting water inside of the affected ear(s) during treatment with ciprofloxacin and hydrocortisone. Care should be used while bathing and swimming may not be recommended. Talk to your healthcare provider.

Ciprofloxacin and hydrocortisone otic side effects


Stop using ciprofloxacin and hydrocortisone otic and seek emergency medical attention or notify your doctor if you experience:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);




  • skin rash; or




  • ear drainage, discharge, or worsening pain.



Other less serious side effects may also occur such as headache or itching in the ear. Continue to use the medication and talk to your doctor if these side effects seem excessive or unusual.


Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.


Ciprofloxacin and hydrocortisone otic Dosing Information


Usual Adult Dose for Acute Otitis Externa:

3 drops into the affected ear twice daily for 7 days

Usual Pediatric Dose for Acute Otitis Externa:

3 drops into the affected ear twice daily for 7 days.


What other drugs will affect my ciprofloxacin and hydrocortisone otic?


Do not use other ear drops during treatment with ciprofloxacin and hydrocortisone otic without first talking to your doctor.

Drugs other than those listed here may also interact with ciprofloxacin and hydrocortisone otic. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.



More ciprofloxacin and hydrocortisone otic resources


  • Ciprofloxacin and hydrocortisone otic Side Effects (in more detail)
  • Ciprofloxacin and hydrocortisone otic Dosage
  • Ciprofloxacin and hydrocortisone otic Use in Pregnancy & Breastfeeding
  • Ciprofloxacin and hydrocortisone otic Support Group
  • 0 Reviews for Ciprofloxacin and hydrocortisone - Add your own review/rating


Compare ciprofloxacin and hydrocortisone otic with other medications


  • Acute Otitis Externa


Where can I get more information?


  • Your pharmacist has more information about ciprofloxacin and hydrocortisone otic written for health professionals that you may read.

See also: ciprofloxacin and hydrocortisone side effects (in more detail)


C1 Esterase Inhibitor (Human)


Pronunciation: C1 ES-ter-ase in-HIB-i-ter
Generic Name: C1 Esterase Inhibitor (Human)
Brand Name: Cinryze


C1 Esterase Inhibitor (Human) is used for:

Preventing angioedema attacks in teenagers and adults with hereditary angioedema (HAE).


C1 Esterase Inhibitor (Human) is a C1 esterase inhibitor (human). It works by helping to control inflammation and parts of the immune system. This helps to prevent the swelling and/or painful attacks that occur with HAE.


Do NOT use C1 Esterase Inhibitor (Human) if:


  • you are allergic to any ingredient in C1 Esterase Inhibitor (Human)

Contact your doctor or health care provider right away if any of these apply to you.



Before using C1 Esterase Inhibitor (Human):


Some medical conditions may interact with C1 Esterase Inhibitor (Human). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of blood clotting problems, such as blood clots in your veins or lungs (eg, deep vein thrombosis, pulmonary embolism)

Some MEDICINES MAY INTERACT with C1 Esterase Inhibitor (Human). However, no specific interactions with C1 Esterase Inhibitor (Human) are known at this time.


Ask your health care provider if C1 Esterase Inhibitor (Human) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use C1 Esterase Inhibitor (Human):


Use C1 Esterase Inhibitor (Human) as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with C1 Esterase Inhibitor (Human). Talk to your pharmacist if you have questions about this information.

  • C1 Esterase Inhibitor (Human) may be given as an injection at your doctor's office, hospital, or clinic. If you will be using C1 Esterase Inhibitor (Human) at home, a health care provider will teach you how to use it. Be sure you understand how to use C1 Esterase Inhibitor (Human). Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

  • After mixing, C1 Esterase Inhibitor (Human) should be colorless to slightly blue. Do not use C1 Esterase Inhibitor (Human) if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

  • C1 Esterase Inhibitor (Human) must be mixed before use. Use within 3 hours after mixing.

  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

  • If you miss a dose of C1 Esterase Inhibitor (Human), contact your doctor right away.

Ask your health care provider any questions you may have about how to use C1 Esterase Inhibitor (Human).



Important safety information:


  • C1 Esterase Inhibitor (Human) may contain albumin, which comes from human blood. There is a very rare risk of getting a viral disease or a central nervous system disease called Creutzfeldt-Jakob disease from products with albumin. No cases of these problems have been found in patients who have used C1 Esterase Inhibitor (Human).

  • The risk of blood clots (eg, in your veins or lungs) may be increased with high doses of C1 Esterase Inhibitor (Human). Tell your doctor if you have a history of blood clotting problems. Contact your doctor right away if you develop symptoms of a blood clot (eg, changes in consciousness, speech, or vision; one-sided weakness or loss of muscle control; severe or persistent headache; chest pain; shortness of breath; pain, numbness, or swelling in your arms or legs) while you are using C1 Esterase Inhibitor (Human). Talk with your doctor for more information.

  • C1 Esterase Inhibitor (Human) should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: It is not known if C1 Esterase Inhibitor (Human) can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using C1 Esterase Inhibitor (Human) while you are pregnant. It is not known if C1 Esterase Inhibitor (Human) is found in breast milk. If you are or will be breast-feeding while you use C1 Esterase Inhibitor (Human), check with your doctor. Discuss any possible risks to your baby.


Possible side effects of C1 Esterase Inhibitor (Human):


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Headache; stuffy or runny nose.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing or shortness of breath; tightness in the chest; fast heartbeat; severe dizziness or lightheadedness; fainting; swelling of the mouth, face, lips, or tongue; blue lips or gums; wheezing); symptoms of infection (eg, fever, sore throat, cough).



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: C1 Esterase Inhibitor (Human) side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include changes in consciousness, speech, or vision; chest pain; one-sided weakness or loss of muscle control; pain, numbness, or swelling in your arms or legs; severe or persistent headache; shortness of breath.


Proper storage of C1 Esterase Inhibitor (Human):

Store C1 Esterase Inhibitor (Human) in the refrigerator or at room temperature, between 36 and 77 degrees F (2 and 25 degrees C). Do not freeze. Store in original packaging until just before use. Do not use C1 Esterase Inhibitor (Human) if the expiration date has passed. After mixing, you may store C1 Esterase Inhibitor (Human) at room temperature for up to 3 hours. If you do not use it within 3 hours after mixing, throw it away. Keep C1 Esterase Inhibitor (Human) out of the reach of children and away from pets.


General information:


  • If you have any questions about C1 Esterase Inhibitor (Human), please talk with your doctor, pharmacist, or other health care provider.

  • C1 Esterase Inhibitor (Human) is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about C1 Esterase Inhibitor (Human). If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More C1 Esterase Inhibitor (Human) resources


  • C1 Esterase Inhibitor (Human) Side Effects (in more detail)
  • C1 Esterase Inhibitor (Human) Use in Pregnancy & Breastfeeding
  • C1 Esterase Inhibitor (Human) Support Group
  • 3 Reviews for C1 Esterase Inhibitor (Human) - Add your own review/rating


Compare C1 Esterase Inhibitor (Human) with other medications


  • Hereditary Angioedema

Clobevate


Generic Name: clobetasol topical (kloe BAY ta sol)

Brand Names: Clobevate, Clobex, Cormax, Embeline E, Olux, Olux-E, Temovate


What is Clobevate (clobetasol topical)?

Clobetasol is a topical (for the skin) steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.


Clobetasol topical is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.


Clobetasol topical may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Clobevate (clobetasol topical)?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with clobetasol topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Do not use this medication on a child without medical advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period. Contact your doctor if your condition does not improve within 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection.

What should I discuss with my healthcare provider before using Clobevate (clobetasol topical)?


Do not use this medication if you are allergic to clobetasol.

To make sure you can safely take clobetasol topical, tell your doctor if you are allergic to any drugs, or if you have any type of skin infection.


Also tell your doctor if you have diabetes. Topical steroid medicines absorbed through the skin may increase the glucose (sugar) levels in your blood or urine.


FDA pregnancy category C. It is not known whether clobetasol topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether clobetasol topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication on a child without medical advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period.

How should I use Clobevate (clobetasol topical)?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.


Wash your hands before and after using clobetasol topical, unless you are using the medication to treat the skin on your hands.

Apply a small amount to the affected area and rub it gently into the skin. Do not use this medication over a large area of skin.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with clobetasol topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Contact your doctor if your condition does not improve within 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection. It is important to use clobetasol topical regularly to get the most benefit.

If you use this medication long-term, your blood will need to be tested often. Visit your doctor regularly.


Store at room temperature away from moisture and heat. Keep from freezing.

What happens if I miss a dose?


Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of clobetasol is not expected to produce life-threatening symptoms. However, long-term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


What should I avoid while using Clobevate (clobetasol topical)?


Clobetasol topical should not be used to treat any skin condition your doctor has not prescribed it for.


Avoid using clobetasol topical to treat skin on your face, underarms, or groin area without your doctor's advice. Avoid getting this medication in your eyes. If contact does occur, rinse with water. Do not use clobetasol topical on broken or infected skin. Also avoid using this medication in open wounds.

Clobevate (clobetasol topical) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when clobetasol topical is applied to the skin, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream.


Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing clobetasol topical through your skin, such as:

  • blurred vision, or seeing halos around lights;




  • mood changes;




  • sleep problems (insomnia);




  • weight gain, puffiness in your face; or




  • muscle weakness, feeling tired.



Less serious side effects may include:



  • mild skin rash, itching, burning, or redness;




  • dry or cracking skin;




  • thinning or softening of your skin;




  • skin rash or irritation around your mouth;




  • swollen hair follicles;




  • temporary hair loss;




  • spider veins;




  • changes in color of treated skin;




  • blisters, pimples, or crusting of treated skin; or




  • stretch marks.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Clobevate (clobetasol topical)?


It is not likely that other drugs you take orally or inject will have an effect on topically applied clobetasol topical. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Clobevate resources


  • Clobevate Side Effects (in more detail)
  • Clobevate Use in Pregnancy & Breastfeeding
  • Clobevate Drug Interactions
  • Clobevate Support Group
  • 0 Reviews for Clobevate - Add your own review/rating


  • Clobevate Advanced Consumer (Micromedex) - Includes Dosage Information

  • Clobex Lotion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Clobex Prescribing Information (FDA)

  • Cormax Prescribing Information (FDA)

  • Embeline Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Olux Prescribing Information (FDA)

  • Olux Foam MedFacts Consumer Leaflet (Wolters Kluwer)

  • Olux-E Prescribing Information (FDA)

  • Olux-E Emollient Foam MedFacts Consumer Leaflet (Wolters Kluwer)

  • Temovate Prescribing Information (FDA)



Compare Clobevate with other medications


  • Atopic Dermatitis
  • Dermatitis
  • Lichen Planus
  • Lichen Sclerosus
  • Psoriasis


Where can I get more information?


  • Your pharmacist can provide more information about clobetasol topical.

See also: Clobevate side effects (in more detail)


Clenia Emollient Cream


Generic Name: sulfacetamide sodium and sulfur topical (SUL fa SEET a mide SOE dee um and SUL fur TOP i kal)

Brand Names: Avar Cleanser, Avar Gel, Avar LS Cleanser, Avar-E, Avar-E Emollient, Avar-E Green, Avar-e LS, BP 10-Wash, Clarifoam EF, Clenia Emollient Cream, Clenia Foaming Wash, Plexion , Plexion Cleanser, Plexion Cleansing Cloths, Plexion SCT, Prascion, Prascion Cleanser, Prascion FC Cloths, Prascion RA, Rosac, Rosac Wash, Rosaderm Cleanser, Rosanil Cleanser, Rosula, SE 10-5 SS, Sulfacet-R, Sulfatol C, Sulfatol SS, SulZee Wash, Sumaxin, Sumaxin TS, Sumaxin Wash, Suphera, Topisulf, Zencia Wash, Zetacet


What is Clenia Emollient Cream (sulfacetamide sodium and sulfur topical)?

Sulfacetamide sodium and sulfur are antibiotic that fight bacteria.


The combination of sulfacetamide sodium and sulfur topical (for the skin) is used to treat acne, rosacea, and seborrheic dermatitis (a red, flaking skin rash).


Sulfacetamide sodium and sulfur topical may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Clenia Emollient Cream (sulfacetamide sodium and sulfur topical)?


You should not use this medication if you are allergy to sulfa drugs or if you have kidney disease. Avoid getting this medication in your eyes, nose, or mouth. If this does happen, rinse with water.

Do not cover the treated skin area unless your doctor has told you to.


Avoid using other medications on the areas you treat with sulfacetamide sodium and sulfur topical unless you doctor tells you to.

What should I discuss with my healthcare provider before using Clenia Emollient Cream (sulfacetamide sodium and sulfur topical)?


You should not use this medication if you are allergy to sulfa drugs or if you have kidney disease.

To make sure you can safely use this medication, tell your doctor about all of your medical conditions.


FDA pregnancy category C. It is not known whether sulfacetamide sodium and sulfur topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether sulfacetamide sodium and sulfur topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Clenia Emollient Cream (sulfacetamide sodium and sulfur topical)?


Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


Wash your hands before and after applying this medication.

Do not cover the treated skin area unless your doctor has told you to.


Use this medication regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.


Store at room temperature away from moisture and heat.

What happens if I miss a dose?


Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


What should I avoid while using Clenia Emollient Cream (sulfacetamide sodium and sulfur topical)?


Avoid getting this medication in your eyes, nose, or mouth. If this does happen, rinse with water. Do not use sulfacetamide sodium and sulfur topical on sunburned, windburned, dry, chapped, irritated, or broken skin.

Avoid using other medications on the areas you treat with sulfacetamide sodium and sulfur topical unless you doctor tells you to.


Clenia Emollient Cream (sulfacetamide sodium and sulfur topical) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • new or worsening skin rash;




  • joint pain;




  • fever; or




  • mouth sores.



Less serious side effects may include redness, warmth, swelling, itching, stinging, burning, or irritation of treated skin.


This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Clenia Emollient Cream (sulfacetamide sodium and sulfur topical)?


It is not likely that other drugs you take orally or inject will have an effect on topically applied sulfacetamide sodium and sulfur. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Clenia Emollient Cream resources


  • Clenia Emollient Cream Side Effects (in more detail)
  • Clenia Emollient Cream Use in Pregnancy & Breastfeeding
  • Clenia Emollient Cream Drug Interactions
  • Clenia Emollient Cream Support Group
  • 0 Reviews for Clenia Emollient - Add your own review/rating


  • Avar LS Cleanser MedFacts Consumer Leaflet (Wolters Kluwer)

  • Clarifoam EF Foam MedFacts Consumer Leaflet (Wolters Kluwer)

  • Clarifoam EF Prescribing Information (FDA)

  • Plexion Prescribing Information (FDA)

  • Plexion Cleansing Cloths MedFacts Consumer Leaflet (Wolters Kluwer)

  • Plexion SCT Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Plexion TS Emulsion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Prascion Cleanser Prescribing Information (FDA)

  • Rosac Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Rosaderm Cleanser Prescribing Information (FDA)

  • Rosanil Cleanser Prescribing Information (FDA)

  • Rosula Foam MedFacts Consumer Leaflet (Wolters Kluwer)

  • Rosula Prescribing Information (FDA)

  • Rosula Cleanser Emulsion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Sumadan MedFacts Consumer Leaflet (Wolters Kluwer)

  • Sumadan Wash Prescribing Information (FDA)

  • Sumaxin Wash MedFacts Consumer Leaflet (Wolters Kluwer)

  • Sumaxin Wash Prescribing Information (FDA)

  • Zencia Wash Prescribing Information (FDA)



Compare Clenia Emollient Cream with other medications


  • Acne
  • Rosacea
  • Seborrheic Dermatitis


Where can I get more information?


  • Your pharmacist can provide more information about sulfacetamide sodium and sulfur topical.

See also: Clenia Emollient side effects (in more detail)


Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid


Pronunciation: klor-fen-EER-a-meen/dex-troe-meth-OR-fan/fen-ill-EF-rin
Generic Name: Chlorpheniramine/Dextromethorphan/Phenylephrine
Brand Name: Examples include Poly-Tussin DM and Ceron-DM


Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid is used for:

Relieving sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.


Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid is a decongestant, antihistamine, and cough suppressant combination. It works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking histamine, which helps reduce symptoms, such as watery eyes and sneezing, while the cough suppressant works in the brain to help decrease the cough reflex.


Do NOT use Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid if:


  • you are allergic to any ingredient in Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid

  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems

  • you are unable to urinate or are having an asthma attack

  • you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid:


Some medical conditions may interact with Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, plan to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a fast, slow, or irregular heartbeat

  • if you have a history of adrenal gland problems (eg, tumor); heart problems; high blood pressure; diabetes; heart blood vessel problems; stroke; glaucoma; a blockage of your stomach, intestines, or bladder; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; or an overactive thyroid

  • if you have a history of asthma, chronic cough, chronic obstructive pulmonary disease (COPD), or other lung problems (eg, chronic bronchitis, emphysema), or if your cough produces large amounts of mucus

Some MEDICINES MAY INTERACT with Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid may be increased

  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased

  • Bromocriptine or hydantoins (eg, phenytoin) because side effects may be increased by Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid

  • Guanadrel, guanethidine, methyldopa, mecamylamine, or reserpine because their effectiveness may be decreased by Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid:


Use Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid may be taken with or without food.

  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • If you miss a dose of Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid.



Important safety information:


  • Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid. Using Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Do not take diet or appetite control medicines while you are taking Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid without checking with your doctor.

  • Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid contains phenylephrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains phenylephrine. If it does or if you are uncertain, contact your doctor or pharmacist.

  • Do NOT exceed the recommended dose or take Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid for longer than prescribed without checking with your doctor.

  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.

  • Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid. Use a sunscreen or protective clothing if you must be outside for a prolonged period.

  • If you are scheduled for allergy skin testing, do not take Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid for several days before the test because it may decrease your response to the skin tests.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid.

  • Use Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid with caution in the ELDERLY because they may be more sensitive to its effects.

  • Caution is advised when using Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid, discuss with your doctor the benefits and risks of using Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid during pregnancy. It is unknown if Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid is excreted in breast milk. Do not breast-feed while taking Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid.


Possible side effects of Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch .


See also: Chlorpheniramine/Dextromethorphan/Phenylephrine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; severe dizziness, lightheadedness, or headache; severe drowsiness; seizures; unusually fast, slow, or irregular heartbeat; vomiting.


Proper storage of Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid:

Store Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid out of the reach of children and away from pets.


General information:


  • If you have any questions about Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid, please talk with your doctor, pharmacist, or other health care provider.

  • Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Chlorpheniramine/Dextromethorphan/Phenylephrine Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Chlorpheniramine/Dextromethorphan/Phenylephrine resources


  • Chlorpheniramine/Dextromethorphan/Phenylephrine Side Effects (in more detail)
  • Chlorpheniramine/Dextromethorphan/Phenylephrine Use in Pregnancy & Breastfeeding
  • Chlorpheniramine/Dextromethorphan/Phenylephrine Drug Interactions
  • Chlorpheniramine/Dextromethorphan/Phenylephrine Support Group
  • 6 Reviews for Chlorpheniramine/Dextromethorphan/Phenylephrine - Add your own review/rating


Compare Chlorpheniramine/Dextromethorphan/Phenylephrine with other medications


  • Cough and Nasal Congestion

Chlorpheniramine/Dextromethorphan/Phenylephrine


Pronunciation: klor-fen-IR-a-meen/dex-troe-meth-OR-fan/fen-ill-EF-rin
Generic Name: Chlorpheniramine/Dextromethorphan/Phenylephrine
Brand Name: Maxiphen ADT


Chlorpheniramine/Dextromethorphan/Phenylephrine is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.


Chlorpheniramine/Dextromethorphan/Phenylephrine is a decongestant, antihistamine, and cough suppressant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing while the cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.


Do NOT use Chlorpheniramine/Dextromethorphan/Phenylephrine if:


  • you are allergic to any ingredient in Chlorpheniramine/Dextromethorphan/Phenylephrine

  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems

  • you are unable to urinate or are having an asthma attack

  • you take sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Chlorpheniramine/Dextromethorphan/Phenylephrine:


Some medical conditions may interact with Chlorpheniramine/Dextromethorphan/Phenylephrine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, plan to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a fast, slow, or irregular heartbeat

  • if you have a history of adrenal gland problems (eg, adrenal gland tumor); heart problems; high blood pressure; diabetes; heart blood vessel problems; stroke; glaucoma; a blockage of your bladder, stomach, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; or an overactive thyroid

  • if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with Chlorpheniramine/Dextromethorphan/Phenylephrine. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Chlorpheniramine/Dextromethorphan/Phenylephrine may be increased

  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased

  • Bromocriptine or hydantoins (eg, phenytoin) because side effects may be increased by Chlorpheniramine/Dextromethorphan/Phenylephrine

  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because effectiveness may be decreased by Chlorpheniramine/Dextromethorphan/Phenylephrine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Chlorpheniramine/Dextromethorphan/Phenylephrine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Chlorpheniramine/Dextromethorphan/Phenylephrine:


Use Chlorpheniramine/Dextromethorphan/Phenylephrine as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Chlorpheniramine/Dextromethorphan/Phenylephrine may be taken with or without food.

  • If you miss a dose of Chlorpheniramine/Dextromethorphan/Phenylephrine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Chlorpheniramine/Dextromethorphan/Phenylephrine.



Important safety information:


  • Chlorpheniramine/Dextromethorphan/Phenylephrine may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Chlorpheniramine/Dextromethorphan/Phenylephrine. Using Chlorpheniramine/Dextromethorphan/Phenylephrine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Do not take diet or appetite control medicines while you are taking Chlorpheniramine/Dextromethorphan/Phenylephrine without checking with your doctor.

  • Chlorpheniramine/Dextromethorphan/Phenylephrine contains chlorpheniramine, dextromethorphan, and phenylephrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains chlorpheniramine, dextromethorphan, or phenylephrine. If it does or if you are uncertain, contact your doctor or pharmacist.

  • Do NOT exceed the recommended dose or take Chlorpheniramine/Dextromethorphan/Phenylephrine for longer than prescribed without checking with your doctor.

  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.

  • Chlorpheniramine/Dextromethorphan/Phenylephrine may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Chlorpheniramine/Dextromethorphan/Phenylephrine. Use a sunscreen or protective clothing if you must be outside for a prolonged period.

  • If you are scheduled for allergy skin testing, do not take Chlorpheniramine/Dextromethorphan/Phenylephrine for several days before the test because it may decrease your response to the skin tests.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Chlorpheniramine/Dextromethorphan/Phenylephrine.

  • Use Chlorpheniramine/Dextromethorphan/Phenylephrine with caution in the ELDERLY because they may be more sensitive to its effects.

  • Caution is advised when using Chlorpheniramine/Dextromethorphan/Phenylephrine in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Chlorpheniramine/Dextromethorphan/Phenylephrine, discuss with your doctor the benefits and risks of using Chlorpheniramine/Dextromethorphan/Phenylephrine during pregnancy. It is unknown if Chlorpheniramine/Dextromethorphan/Phenylephrine is excreted in breast milk. Do not breast-feed while taking Chlorpheniramine/Dextromethorphan/Phenylephrine.


Possible side effects of Chlorpheniramine/Dextromethorphan/Phenylephrine:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Chlorpheniramine/Dextromethorphan/Phenylephrine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.


Proper storage of Chlorpheniramine/Dextromethorphan/Phenylephrine:

Store Chlorpheniramine/Dextromethorphan/Phenylephrine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Chlorpheniramine/Dextromethorphan/Phenylephrine out of the reach of children and away from pets.


General information:


  • If you have any questions about Chlorpheniramine/Dextromethorphan/Phenylephrine, please talk with your doctor, pharmacist, or other health care provider.

  • Chlorpheniramine/Dextromethorphan/Phenylephrine is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Chlorpheniramine/Dextromethorphan/Phenylephrine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Chlorpheniramine/Dextromethorphan/Phenylephrine resources


  • Chlorpheniramine/Dextromethorphan/Phenylephrine Side Effects (in more detail)
  • Chlorpheniramine/Dextromethorphan/Phenylephrine Use in Pregnancy & Breastfeeding
  • Chlorpheniramine/Dextromethorphan/Phenylephrine Drug Interactions
  • Chlorpheniramine/Dextromethorphan/Phenylephrine Support Group
  • 6 Reviews for Chlorpheniramine/Dextromethorphan/Phenylephrine - Add your own review/rating


  • Alka-Seltzer Plus Cold and Cough Concise Consumer Information (Cerner Multum)

  • Quartuss DM Prescribing Information (FDA)

  • Trital DM Prescribing Information (FDA)



Compare Chlorpheniramine/Dextromethorphan/Phenylephrine with other medications


  • Cough and Nasal Congestion

Cobal-1000 injection


Generic Name: cyanocobalamin (injection) (sye AN oh koe BAL a min)

Brand Names: Cobolin-M, Cyomin, Depo-Cobolin, Vitamin B-12, Vitamin B12


What is Cobal-1000 (cyanocobalamin (injection))?

Cyanocobalamin is a man-made form of vitamin B12. Vitamin B12 is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.


Cyanocobalamin is used to treat vitamin B12 deficiency in people with pernicious anemia and other conditions.


Cyanocobalamin may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Cobal-1000 (cyanocobalamin (injection))?


You should not use this medication if you are allergic to cobalt, or if you have Leber's disease. Cyanocobalamin can lead to optic nerve damage (and possibly blindness) in people with Leber's disease.

To treat pernicious anemia, you will have to use this medication on a regular basis for the rest of your life. Not using the medication can lead to irreversible nerve damage in your spinal cord.


Pernicious anemia is also treated with folic acid to help maintain red blood cells. However, folic acid will not treat Vitamin B12 deficiency and will not prevent possible damage to the spinal cord. Take all of your medications as directed.


Your dose needs may change if you become pregnant, if you breast-feed, or if you eat a vegetarian diet. Tell your doctor about any changes in your diet or medical condition.

What should I discuss with my healthcare provider before using Cobal-1000 (cyanocobalamin (injection))?


You should not use this medication if you are allergic to cobalt, or if you have Leber's disease. Cyanocobalamin can lead to optic nerve damage (and possibly blindness) in people with Leber's disease.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use cyanocobalamin injection:



  • any type of infection;




  • iron or folic acid deficiency;




  • kidney or liver disease; or




  • if you are receiving any medication or treatment that affects bone marrow.




FDA pregnancy category C. It is not known whether cyanocobalamin injection is harmful to an unborn baby. Before using this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Cyanocobalamin passes into breast milk, but it is not known whether cyanocobalamin could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Cobal-1000 (cyanocobalamin (injection))?


Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.


Your dose needs may change if you become pregnant, if you breast-feed, or if you eat a vegetarian diet. Tell your doctor about any changes in your diet or medical condition.

The injection form is given as a shot into a muscle or under the skin. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to inject your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.


Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.


To be sure this medication is helping your condition, your blood will need to be tested every 3 to 6 months. This will help your doctor determine the correct dose and how long to treat you with cyanocobalamin. Do not miss any scheduled appointments.


To treat pernicious anemia, you will have to use this medication on a regular basis for the rest of your life. Not using the medication can lead to irreversible nerve damage in your spinal cord.


Pernicious anemia is also treated with folic acid to help maintain red blood cells. However, folic acid will not treat Vitamin B12 deficiency and will not prevent possible damage to the spinal cord. Take all of your medications as directed.


Store this medication at room temperature away from moisture, heat, and light.

What happens if I miss a dose?


Call your doctor for instructions if you miss a dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of cyanocobalamin is not likely to cause life-threatening symptoms.

What should I avoid while using Cobal-1000 (cyanocobalamin (injection))?


Avoid drinking large amounts of alcohol while you are being treated with cyanocobalamin.

Cobal-1000 (cyanocobalamin (injection)) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • chest pain;




  • feeling short of breath, even with mild exertion;




  • swelling, rapid weight gain; or




  • unusual warmth, redness, or pain in an arm or leg.



Less serious side effects may include:



  • headache, dizziness, weakness;




  • nausea, upset stomach, diarrhea;




  • numbness or tingling;




  • pain, swelling, redness, or irritation where the injection was given;




  • fever;




  • joint pain; or




  • itching or rash.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Cobal-1000 (cyanocobalamin (injection))?


Before using cyanocobalamin, tell your doctor if you are taking any of the following medications:



  • antibiotics;




  • methotrexate (Rheumatrex);




  • pyrimethamine (Daraprim);




  • colchicine; or




  • if you drank a lot of alcohol within the past 2 weeks.



This list is not complete and there may be other drugs that can interact with cyanocobalamin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.


Where can I get more information injection?


  • Your pharmacist can provide more information about cyanocobalamin.

See also: Cobal-1000 side effects (in more detail)



More Cobal-1000 resources


  • Cobal-1000 Side Effects (in more detail)
  • Cobal-1000 Use in Pregnancy & Breastfeeding
  • Cobal-1000 Drug Interactions
  • 0 Reviews for Cobal-1000 - Add your own review/rating


Compare Cobal-1000 with other medications


  • B12 Nutritional Deficiency
  • Pernicious Anemia
  • Schilling Test
  • Vitamin B12 Deficiency